New evidence suggests that if you have red hair, you are more resistant to local anesthetics. Studies about red heads and anesthetics arose from an urban legend of sorts that circulated in the anesthesiologist community, claiming that people with red hair were more difficult to fully numb for procedures. Surprisingly enough, scientists found substantial evidence to support the claim.
It may be that this phenomenon occurs as a result of gene mutations. The gene in question is called the MC1R gene, which produces melanin in dark haired and blonde people. When a specific mutation to this gene takes place, it produces a chemical called pheomelanin, which causes red hair and fair skin. In addition to producing these chemicals that determine hair/skin tone, MC1R also belongs to a family of receptors that receive pain signals in the brain. Research leads scientists to believe that this mutation that causes the production of pheomelanin also creates a heightened sensitivity to pain. It’s also worth mentioning that this particular gene mutation does exist in non-redheads, but in much lower proportions (97% of tested redheads had the mutation, whereas it was only present in 26% of tested non-gingers).
So, if you or someone close to you has red hair, awareness is the key! Don’t be afraid to mention any concerns about dental anesthetics to your healthcare professionals. They may be able to give you a little more anesthetic if you are resistant to getting properly numbed or have any concerns about it!
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